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"description": "EMPATECT® 10 mg film-coated tablets\nEMPATECT® 25 mg film-coated tablets \nEMPATECT M -12.5mg/500mg tablets\nempagliflozin / Metrformin\n\n\nWhat Empatect is and what it is used for\nWhat Empatect is\nEmpatect contains the active substance empagliflozin.\nEmpatect is a member of a group of medicines called sodium glucose co-transporter-2 (SGLT2)\ninhibitors.\nWhat Empatect is used for\nType 2 diabetes mellitus\nEmpatect is used to treat type 2 diabetes in adults and children aged 10 years and older that\ncannot be controlled by diet and exercise alone.\n•Empatect can be used without other medicines in patients who cannot take metformin (another\ndiabetes medicine).\n•Empatect can also be used with other medicines for the treatment of diabetes. These may be\nmedicines taken by mouth or given by injection such as insulin.\nEmpatect works by blocking the SGLT2 protein in your kidneys. This causes blood sugar (glucose) to\nbe removed in your urine. There by Empatect lowers the amount of sugar in your blood.\nThis medicine can also help prevent heart disease in patients with type 2 diabetes mellitus.\nIt is important that you continue with your diet and exercise plan as told by your doctor, pharmacist or\nnurse.\nHeart failure\n•Empatect is used to treat heart failure in adult patients with symptoms due to impaired heart\nfunction.\nChronic kidney disease\n•Empatect is used to treat chronic kidney disease in adult patients.\nWhat is type 2 diabetes?\nType 2 diabetes is a disease that comes from both your genes and your lifestyle. If you have type 2\ndiabetes, your pancreas does not make enough insulin to control the level of glucose in your blood,\nand your body is unable to use its own insulin effectively. This results in high levels of glucose in your\nblood which can lead to medical problems like heart disease, kidney disease, blindness, and poor\ncirculation in your limbs.\nWhat is heart failure?\nHeart failure occurs when the heart is too weak or stiff and cannot work properly. This can lead to\nserious medical problems and need for hospital care. The most common symptoms of heart failure are\nfeeling breathless, feeling tired or very tired all the time, and ankle swelling.\nEmpatect helps protect your heart from getting weaker and improves your symptoms.\nWhat is chronic kidney disease?\nChronic kidney disease is a long-term condition. It might be caused by other diseases such as diabetes\nand high blood pressure or even by your own immune system attacking the kidneys. When you have\nchronic kidney disease, your kidneys may gradually lose their ability to clean and filter the blood\nproperly. This can lead to serious medical problems such as swollen legs, heart failure or need for\nhospital care.\nEmpatect helps protect your kidneys from losing their function.\n2. What you need to know before you take Empatect\nDo not take Empatect\n• if you are allergic to empagliflozin or any of the other ingredients of this medicine (listed in\nsection 6).\nWarnings and precautions\nContact a doctor or the nearest hospital straight away:\nKetoacidosis\n• if you experience rapid weight loss, feeling sick or being sick, stomach pain, excessive thirst,\nfast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to your breath,\na sweet or metallic taste in your mouth, or a different odour to your urine or sweat, contact a\ndoctor or the nearest hospital straight away. These symptoms could be a sign of “ketoacidosis”\n– a serious, sometimes life-threatening problem you can get because of increased levels of\n“ketone bodies” in your urine or blood, seen in tests. The risk of developing ketoacidosis may\nbe increased with prolonged fasting, excessive alcohol consumption, dehydration, sudden\nreductions in insulin dose, or a higher need of insulin due to major surgery or serious illness.\nIf you suspect you have ketoacidosis, contact a doctor or the nearest hospital straight away and stop\ntaking this medicine until further advice from your doctor.\nTalk to your doctor, pharmacist or nurse before taking this medicine, and during treatment:\n• if you have “type 1 diabetes”. This type usually starts when you are young and your body does\nnot produce any insulin. You should not take Empatect if you have type 1 diabetes.\n• if you have serious kidney problems – your doctor may limit your dose to 10 mg once a day or\nask you to take a different medicine (see also section 3, ‘How to take Empatect’).\n• if you have serious liver problems – your doctor may ask you to take a different medicine.\n• might be at risk of dehydration, for example:\no if you are being sick, have diarrhoea or fever, or if you are not able to eat or drink\no if you are taking medicines that increase urine production [diuretics] or lower blood\npressure\no if you are 75 years old or older.\nPossible side effects\nLike all medicines, this medicine can cause side effects, although not everybody gets them.\nContact a doctor or the nearest hospital straight away if you have any of the following side\neffects:\nSevere a",
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"description": "RODUCT INTRODUCTION\nPANTECT 40mg Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux, peptic ulcer disease, Zollinger-Ellison syndrome. It provides relief from symptoms and promotes healing.\n\nPANTECT 40mg Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Your doctor will decide the duration of treatment but you should keep on taking it as prescribed, even if your symptoms disappear quickly. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.\n\nThe most common side effects observed with this medicine include nausea, vomiting, headache, dizziness, flatulence, diarrhea, stomach pain, and thrombophlebitis (pain, redness, and swelling of the vein). These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Long-term use of this medicine may lead to an increased risk of side effects. For instance, using this medicine for more than 1 year may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.\n\nPANTECT 40mg Injection is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.\n________________________________________\nUSES OF PANTECT INJECTION\n•\tAcidity\n•\tGastroesophageal reflux disease (Acid reflux)\n•\tPeptic ulcer disease\n•\tTreatment of Zollinger-Ellison syndrome\nBENEFITS OF PANTECT INJECTION\nIn Treatment of Zollinger-Ellison syndrome\nZollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. PANTECT 40mg Injection By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.\n________________________________________\nSIDE EFFECTS OF PANTECT INJECTION\nMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them\nCommon side effects of PANTECT\n•\tDiarrhea\n•\tFlatulence\n•\tHeadache\n•\tJoint pain\n•\tNausea\n•\tStomach pain\n•\tVomiting\n•\tDizziness\n•\tThrombophlebitis\n________________________________________\nHOW TO USE PANTECT INJECTION\nYour doctor or nurse will give you this medicine. Kindly do not self administer.\n________________________________________\nHOW PANTECT INJECTION WORKS\nPANTECT 40mg Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which in turn relieves acid-related indigestion and heartburn.\n________________________________________\nSAFETY ADVICE\n \nAlcohol\nUNSAFE\nIt is unsafe to consume alcohol with PANTECT 40mg Injection.\n \nPregnancy\nCONSULT YOUR DOCTOR\nPANTECT 40mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.\n \nBreast feeding\nSAFE IF PRESCRIBED\nPANTECT 40mg Injection is probably safe to use during breastfeeding. 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"description": "1. What Mecobalamin injection is for\nMecobalamin injection is a form of Vitamin B12, an essential vitamin which is needed for the production of red blood cells.\nMecobalamin injection is used to prevent and treat certain types of anemia, including Addisonian pernicious anemia, and other kinds of anemia which result from a deficiency of Vitamin B12.\nIt is also used for a test called the Schilling Test, which measures your ability to absorb Vitamin B12 from the bowel.\n2. Before you are given Mecobalamin injection \nYou should not be given Mecobalamin injection if:\nYou are allergic to the active ingredient, cyanocobalamin\nYou are allergic to any of the other ingredients of Mecobalamin injection (see section 6.)\nYou have a condition called toxic amblyopia (poor vision which may be due to Vitamin B12 deficiency).\nIf any of the above applies to you talk to your doctor or nurse.\nCheck with your doctor before being given Mecobalamin injection if:\nYou are pregnant, planning to become pregnant or breast-feeding\nYou have megaloblastic anemia. This is a blood disorder where you have larger than normal blood cells\nTell your doctor if you are taking any of the following medicines:\nAntibiotics (for treating infections) or antimetabolites (medicines which stop cells dividing, such as mercaptopurine for leukemia), as these treatments may interfere with tests to measure the levels of Vitamin B12 in your blood or urine\nAn antibiotic called chloramphenicol, as you may not respond well to Mecobalamin injection \nOral contraceptives ‘The Pill’\nAny other medicine, including medicines obtained without a prescription.\nIf any of the above applies to you talk to your doctor or nurse.\nPregnancy and breast-feeding\nMecobalamin injection should not be used in pregnancy for treating a kind of anemia called megaloblastic anemia unless you also have a Vitamin B12 deficiency.\nMecobalamin injection is found in breast-milk but it is unlikely that it will harm your baby.\nIf you are pregnant, trying to become pregnant or are breast-feeding, ask your doctor or nurse for advice before being given Mecobalamin injection.\nDriving and using machines\nMecobalamin injection may cause dizziness. If this happens to you, do not drive or use machinery.\n3. How you will be given Mecobalamin injection \nImportant:\nYour doctor will choose the dose that is right for you.\nYou will be given Mecobalamin injection by your doctor or nurse as an injection into a muscle. You may be given it just once or it may be repeated every other day, weekly or monthly, depending on how much your body needs.\nAdults and Children\nTreatment of anemia:\nWithout neurological (nervous system) involvement: Initially, 250 ? 1000 micrograms, every other day for 1 to 2 weeks, then 250 micrograms weekly until the blood tests are normal.\nMaintenance dose: 1000 micrograms every month.\nWith neurological involvement: 1000 micrograms every other day for as long as improvement is noticed.\nMaintenance dose: 1000 micrograms every month.\nPrevention of anemia:\n250 -1000 micrograms every month.\nSchilling Test:\n1000 micrograms.\nMedical check-ups\nWhile you are receiving this medicine, your doctor will want you to have regular blood tests to check your condition. 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Possible side effects\nLike all medicines, Mecobalamin injection can cause side effects, although not everybody gets them.\nStop using Mecobalamin injection and seek immediate medical help if you have an allergic reaction.\nThis includes any of the following symptoms:\nDifficulties in breathing\nSwelling of your eyelids, face or lips\nRash or itching especially those covering your whole body\nCollapse.\nEffects on the heart and blood\nLow blood potassium levels and irregular heartbeat during the early stages of treatment\nThrombocytosis (where you have a high number of platelets in your blood)\nEffects on the eyes and skin\nAcne-like rash\nBlisters\nPain at the site of injection\nThe skin may become hard at the site of injection\nThe skin around the injection site may die.\nEffects on the stomach and bowel\nFeeling unwell or sick\nEffects on the nervous system\nDizziness\nTremor\nOther effects\nFever\nChills\nHot flushes\nPain.\nReporting of side effects\nIf you get any side effects, talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet.\n5. How to store Mecobalamin injection \nKeep this medicine out of the sight and reach of children.\nDo not use Mecobalamin injection after the expiry date on the label.",
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"description": "AZITECT INJ ( AZTREONAM 1GM/ 2GM INJ\nDescription\nAztreonam is an antibiotic that is used to treat infections caused by bacteria. It works by killing bacteria or preventing their growth.\nAztreonam is used to treat bacterial infections in many different parts of the body. It is sometimes given with other antibiotics. This medicine will not work for colds, flu, or other viral infections.\nThis medicine is available only with your doctor's prescription.\nThis product is available in the following dosage forms:\n•\tPowder for Solution\n________________________________________\nBefore Using\nIn deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:\nAllergies\nTell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. 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Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.\nDrug Interactions\nAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.\nUsing this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.\n•\tBupropion\n•\tCholera Vaccine, Live\n•\tHydroxychloroquine\nOther Interactions\nCertain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.\nOther Medical Problems\nThe presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:\n•\tLiver disease—Patients receiving high doses of aztreonam for a long time, who also have severe liver disease, may have an increased chance of side effects\n•\tKidney disease—Patients with kidney disease may have an increased chance of side effects\n\n________________________________________\nProper Use\nTo help clear up your infection completely, aztreonam must be given for the full time of treatment, even if you begin to feel better after a few days. Also, this medicine works best when there is a constant amount in the blood or urine. To help keep the amount constant, aztreonam must be given on a regular schedule.\nDosing\nThe dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. 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"description": "CEFTECT SB\n\nCEFTECT SB is an Antibiotic Adjuvant Entity (AAE) comprising of cefepime\nhydrochloride, a fourth generation cephalosporin, sulbactam sodium, a betalactamase\ninhibitor and a non-antibiotic adjuvant L-arginine. It is available as sterile,\ndry powder for reconstitution before use.\nCefepime hydrochloride, is a semi-synthetic, broad spectrum antibiotic for\nparenteral administration. Cefepime hydrochloride is a white to pale yellow powder\nand a molecular weight of 571.5 g/mol. It is highly soluble in water. Sulbactam\nsodium is a derivative of basic penicillin nucleus. It is an irreversible ß-lactamase\ninhibitor. The molecular weight is 255.22 g/mol. It contains 92 mg sodium per gram.\nL-arginine, at an approximate concentration of 72.5% of TM cefepime is added as\nexcipient. CEFTECT SB is supplied for intramuscular and intravenous administration\nin strengths of 750 mg, 1.5 g and 3.0 g. It is packaged in tubular glass vials.\nIndications\nMainly for the treatment of lower respiratory tract infections (LRTI; Nosocomial and\ncommunity acquired pneumonia), uncomplicated and complicated urinary tract\ninfections (UTI; including pyelonephritis) and mild to moderate bacterial septicemia.\n\nAdditional indications:\nSkin and skin structure infections and severe/complicated intra-abdominal infections\n(including peritonitis and gallbladder infection).\n\n MICROBIOLOGY\nCefepime and sulbactam act synergistically and have a broad spectrum of in vitro\nactivity that encompasses a wide range of ESBL gram positive and gram negative\nbacteria. Cefepime exhibits rapid penetration into gram-negative bacterial cells.\nCefepime and sulbactam combination has been shown to be active against ESBL\nstrains of the following bacteria (including beta-lactamase producing isolates).\nCefepime and Sulbactam have been shown to be active against most strains of the\nfollowing microorganisms both in vitro and in clinical infection.\nAerobes (Gram-negative bacteria):\nEnterobacter, Escherichia coli, Klebsiella pneumoniae, Proteus sp. (including indolepositive\nand indole-negative, Proteus mirabilis), Pseudomonas aeruginosa,\nAcinetobacter calcoaceticus subsp. Woffii, Citrobacter diversus, Citrobacter freundii,\nEnterobacter agglomerans, Haemophilus influenzae, Hafnia alvei, Klebsiella oxytoca,\nMoraxella catarrhalis,Morganella morganii, Proteus vulgaris, Providencia rettgeri,\nProvidencia stuartii, Serratia marcescens, Neisseria meningitidis.\nAerobes (Gram-positive bacteria):\nStaphylococcus aureus (methicillin-susceptible isolates only), Streptococcus\npneumoniae, Streptococcus pyogenes(Lancefield's Group Astreptococci),\nStaphylococcus epidermidis(methicillinsusceptible isolates only), Staphylococcuss\naprophyticus, Streptococcus agalactiae (Lancefield's Group B streptococci).\nAnaerobes (Gram-negative bacteria):\nBacteroides fragilis, Citrobacter diversus, Citrobacter freundil, Providencia species,\nSalmonella species (including S. typhi), Shigella species.\nAnaerobes (Gram-positive bacteria):\nPeptostreptococcus species, Clostridium species, Peptostreptococcus species.\nThe combination agent is useful in the treatment of moderate to severe infections\nparticularly when a ESBLmicrobial etiology is suspected or documented. The\ncombination of cefepime and sulbactam is active against all the organisms sensitive to\ncefepime. In addition, sulbactam itself has the highest intrinsic activity of the betalactamase\ninhibition against the opportunistic pathogen, Acinetobacter baumannii.\nIn addition Sulbactam, has several advantages over Tazobactam. Sulbactam binds with\nplasmid mediated and chromosomal mediated beta-lactamases produced by\nEnterobacteriaceae, whereas Tazobactam binds with only plasmid mediated betalactamases\nproduced by Enterobacteriaceae. Sulbactam displayed highest interaction\nenergy in docking study against CTM-X class of beta-lactamases, whereas Tazobactam\ndisplayed less interaction energy in Docking study against CTM-X class of betalactamases.\nSulbactam has higher intrinsic bacteriostatic property against\nBacteroidesspp., Acinetobacterspp., and N. gonorrhoeae than Tazobactam.\n\nMechanism Of Action\nCEFTECT SB containing cefepime is a bactericidal agent that acts by inhibition of\nbacterial cell wall synthesis. Sulbactam is an irreversible ß-lactamase inhibitor which\nbinds the ß-lactamase enzyme and does not allow it to interact with the antibiotic,\nthus extending their spectrum of activity. It has maximum activity against CTXM\n(Cefotaxime resistant β-lactamases gene) type of class A ß-lactamases, and\nmoderate activity against TEM-β- lactamases gene & SHV-β-lactamases gene. It\ndoes not induce the production of AmpC type class C beta- lactamases.\nSynergistic action\n\nCEFTECT SB containing cefepime and sulbactam is a synergistic antimicrobial\ncombination with marked in vitro antibacterial activity against a broad spectrum of\nESBL (Extended-spectrum beta-lactamase) organisms. Sulbactam not only\npotentiates the antibacterial activity by inhibiting beta-lactamases, ",
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"description": "Generic name: ceftizoxime sodium\nDosage form: Injection\nDrug class: Third generation cephalosporins\n.\nThe usual adult dosage is 1 or 2 grams of Safezox (ceftizoxime injection) in Protectplastic container every 8 to 12 hours. Proper dosage and route of administration should be determined by the condition of the patient, severity of the infection, and susceptibility of the causative organisms.\nBecause of the serious nature of urinary tract infections due to P. aeruginosa and because many strains of Pseudomonas species are only moderately susceptible to Safezox, higher dosage is recommended. Other therapy should be instituted if the response is not prompt.\nA single, 1 gram IM dose is the usual dose for treatment of uncomplicated gonorrhea.\nThe IV route may be preferable for patients with bacterial septicemia, localized parenchymal abscesses (such as intra¬abdominal abscess), peritonitis, or other severe or life¬threatening infections.\nIn those with normal renal function, the IV dosage for such infections is 2 to 12 grams of Safezox (ceftizoxime injection) daily. In conditions such as bacterial septicemia, 6 to 12 grams/day may be given initially by the IV route for several days, and the dosage may then be gradually reduced according to clinical response and laboratory findings.\nPediatric Dosage Schedule\n\tUnit Dose\tFrequency\n\n6 months or older\t50 mg/kg\tq6-8h\nDosage may be increased to a total daily dose of 200 mg/kg (not to exceed the maximum adult dose for serious infection).\n\n",
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"description": "Ceftizoxime sulbactam is helpful in treatment of bacterial infection in the body. Ceftizoxime is an antibiotic that fights various type of bacteria. It stops the growth and multiplication of bacteria, which helps in controlling the infection caused to bacteria.\nWhat are Ceftizoxime Sulbactam Injection?\nSAFETAZOX S is a brand name of Ceftizoxime Sulbactam Injection is helpful in treatment of bacterial infection in the body. Ceftizoxime is an antibiotic that fights various type of bacteria. It stops the growth and multiplication of bacteria, which helps in controlling the infection caused to bacteria.\nSulbactam is a medicine that enhances the effectiveness of ceftizoxime. It blocks an enzyme produced by some bacteria that makes them resistant to antibiotics. By blocking this enzyme, sulbactam helps ceftizoxime to work better against the bacteria. \nThe combination is often used to treat infections in the respiratory tract, urinary tract, skin, and other parts of the body and it is completely safe to buy ceftizoxime sulbactam injection from www.plenumbiotech.com at most affordable price in India.\nUses of Ceftizoxime Sulbactam Injection\nCeftizoxime Sulbactam Injection is a combination medication used to treat various bacterial infections in the body. Some of the common uses are:\n•\tRespiratory Infections: It is used to treat respiratory tract infections such as pneumonia, bronchitis, and lung abscesses.\n•\tUrinary Tract Infections: It is effective against urinary tract infections (UTIs), including bladder infections and kidney infections.\n•\tSkin and Soft Tissue Infections: It may be used to treat skin and soft tissue infections like cellulitis, wound infections, and abscesses.\n•\tIntra-Abdominal Infections: It can be used to treat intra-abdominal infections, including peritonitis (infection of the abdominal lining) and abscesses in the abdominal cavity.\n•\tGynecological Infections: Ceftizoxime sulbactam may be prescribed to treat gynecological infections such as pelvic inflammatory disease (PID) and endometritis (infection of the uterus lining).\n•\tBone and Joint Infections: It can be used in the treatment of bone and joint infections, such as osteomyelitis (bone infection) and septic arthritis (joint infection).\nPrecautions and side effects of Ceftizoxime Sulbactam Injection\n•\tAllergies: Inform your doctor if you are known to allergy to Ceftizoxime sulbactam Injection, other antibiotics, or any other substances. Allergic reactions can be serious and may include symptoms such as rash, itching, swelling, or difficulty breathing. If you experience any signs of an allergic reaction, seek medical help immediately.\n•\tMedical Conditions: Discuss your medical history with your healthcare provider, especially if you have kidney problems, liver disease, or any other health conditions. Injection may require dosage adjustments or additional monitoring in such cases.\n•\tSide Effects: While Ceftizoxime sulbactam injection is generally well-tolerated, it may still cause side effects. Common side effects include nausea, diarrhea, headache, and skin rash. If you experience any unusual or severe side effects, contact your healthcare provider.\nSide effects of Ceftizoxime and Sulbactam for Injection\n•\tPain at the injection site\n•\tSwelling at the injection site\n•\tSkin rash\n•\tDiarrhoea\n•\tAnaphylaxis\n•\tElevated liver enzymes\n•\tNausea\n•\tVomiting\n•\tBlack/tarry stools\nIt’s important to note that the use should be determined by a healthcare professional who will consider factors such as the specific infection, the causative bacteria, and the patient’s individual characteristics and medical history\n",
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"description": "PRODUCT INTRODUCTION\nPolypro7.5 Injection is an antibiotic that fights bacteria. It is used to treat severe bacterial infections of the body. It works by killing and stopping the growth of bacteria that cause these problems. It is commonly used to treat critically ill patients admitted to the hospital.\n\nPolypro7.5 Injection is given under the supervision of a healthcare professional. You should get the injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.\n\nSome people may develop side effects like anaphylactic reaction, kidney damage, neurotoxicity, fever, or pain, redness, and swelling at the site of injection. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away.\n\nBefore starting treatment with this medicine, you should tell your doctor if you are allergic to any antibiotic or have any liver or kidney problems. Pregnant women should consult their doctor before using it. Your doctor may get regular blood tests done to monitor kidney function.\n________________________________________\nUSES OF POLYPROI NJECTION\n•\tTreatment of Severe bacterial infections\nBENEFITS OF POLYPROI NJECTION\nIn Treatment of Severe bacterial infections\nPolypro7.5 Injection is an antibiotic that works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections. This medicine is usually given as an injection by a doctor or nurse and should not be self-administered at home.\n\nThis medicine usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.\n________________________________________\nSIDE EFFECTS OF POLYPRO INJECTION\nMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them\nCommon side effects of Polypro-B\n•\tAnaphylactic reaction\n•\tFever\n•\tKidney damage\n•\tNeurotoxicity\n•\tInjection site reactions (pain, swelling, redness)\n________________________________________\nHOW TO USE POLYPRO INJECTION\nYour doctor or nurse will give you this medicine. Kindly do not self administer.\n________________________________________\nHOW POLYPRO INJECTION WORKS\nPolypro7.5 Injection is an antibiotic. It kills bacteria by destroying the bacterial cell membrane.\n\n",
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"description": "Sulbactam/Cefoperazone 1:1 and 1:2 (1.5gm & 3gm Injection)\n QUALITATIVE AND QUANTITATIVE COMPOSITION Sulbactam sodium I.P./cefoperazone sodium I.P. combination is available as a dry powder for reconstitution in a 1:1 and 1:2 ratio in terms of free Sulbactam /Cefoperazone Sulbactam sodium I.P. is a derivative of the basic penicillin nucleus. It is an irreversible beta-lactamase inhibitor for parenteral use only. Chemically it is sodium penicillinate sulfone. It contains 92 mg sodium (4 mEq) per gram. Sulbactam is an off-white crystalline powder which is highly soluble in water. The molecular weight is 255.22. Cefoperazone sodium I.P. is a semisynthetic broad-spectrum cephalosporin antibiotic for parenteral use only. It contains 34 mg sodium (1.5 mEq) per gram. Cefoperazone is a white crystalline powder which is freely soluble in water. The molecular weight is 667.65. List of Excipients None\n DOSAGE FORM AND STRENGTH Vials of the 1:1 product contain the equivalent of 500 mg + 500 mg and 1000 mg + 1000 mg of sulbactam and cefoperazone, respectively. Vials of the 1:2 product contain the equivalent of 500 mg + 1000 mg and 1000 mg + 2000 mg of sulbactam and cefoperazone, respectively\nTherapeutic Indications Mono-therapy Sulbactam/cefoperazone is indicated for the treatment of the following infections when caused by susceptible organisms: Respiratory Tract Infections Urinary Tract Infections (Upper and Lower) Intra-abdominal Infections Septicemia Meningitis Skin and Soft Tissue Infections Bone and Joint Infections Endometritis Other Infections of the Genital Tract Magnex Forte 1.5 g and Magnex Forte 3.0 g (Vials of the 1:2 product containing the equivalent of 500 mg + 1000 mg and 1000 mg + 2000 mg of sulbactam and cefoperazone, resp.) are indicated for specific subset of patients (immunocompromised febrile neutropenic cancer patients, bone marrow transplant). Concomitant Use Because of the broad-spectrum of activity of sulbactam/cefoperazone, most infections can be treated adequately with this antibiotic alone. However, sulbactam/cefoperazone may be used concomitantly with other antibiotics if such combinations are indicated. If an aminoglycoside is used (see section 8.1 Incompatibilities, Aminoglycosides), renal function should be monitored during the course of therapy (see section \n Posology and Method of Administration, Use in Renal Dysfunction). 4.2 Posology and Method of Administration Sulbactam/Cefoperazone (sulbactam sodium/cefoperazone sodium combination) is available in bottles for parenteral use only. The combination sulbactam sodium/cefoperazone sodium, is available as a dry powder for reconstitution in a 1:1 and 1:2 ratio in terms of free sulbactam and cefoperazone. Vials with a 1:1 ratio contain the equivalent of 500 mg + 500 mg and 1000 mg + 1000 mg of sulbactam and cefoperazone, respectively. Vials with a 1:2 ratio contain the equivalent of 500 mg + 1000 mg and 1000 mg + 2000 mg of sulbactam and cefoperazone, respectively.\nIntravenous Administration For intermittent infusion, each vial of sulbactam/cefoperazone should be reconstituted with the appropriate amount (see section 8.4 Storage and Handling Instructions, Reconstitution) of 5% Dextrose in Water, 0.9% Sodium Chloride Injection or Sterile Water for Injection and then diluted to 20 ml with the same solution followed by administration over 15 to 60 minutes. Lactated Ringer’s Solution is a suitable vehicle for intravenous infusion, however, not for initial reconstitution (see section 8.1 Incompatibilities, Lactated Ringer’s Solution and section 8.4 Storage and Handling Instructions, Lactated Ringer’s Solution). For intravenous injection, each vial should be reconstituted as above and administered over a minimum of 3 minutes. Intramuscular Administration Lidocaine HCl 2% is a suitable vehicle for intramuscular administration, however, not for initial reconstitution (see section 8.1 Incompatibilities, Lidocaine and section 8.4 Storage and Handling Instructions, Lidocaine)\nMechanism of Action The anti-bacterial component of sulbactam/cefoperazone is cefoperazone, a third generation cephalosporin, which acts against sensitive organisms during the stage of active multiplication by inhibiting biosynthesis of cell wall mucopeptide. Sulbactam does not possess any useful antibacterial activity, except against Neisseriaceae and Acinetobacter. However, biochemical studies with cell-free bacterial systems have shown it to be an irreversible inhibitor of most important beta-lactamases produced by beta-lactam antibiotic-resistant organisms. The potential for sulbactam's preventing the destruction of penicillins and cephalosporins by resistant organisms was confirmed in whole-organism studies using resistant strains in which sulbactam exhibited marked synergy with penicillins and cephalosporins. As sulbactam also binds with some penicillin binding proteins, sensitive strains are also often rendered more susceptible to sulbactam/cefoperazone than to cefoperazone",
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